Dr Paul Prentice is CavLab principal investigator and group leader.
Paul’s background is physics, with a dash of astro, which he studied at Queen’s University, Belfast. He eventually landed in Dundee, where he undertook a PhD with Dr Paul Campbell (a fellow Norn Irish lad), Prof Sir Alfred Cuschieri and Prof Kishan Dholakia, at the University of St Andrews. This work developed a holographic optical trapping rig, for tweezing and manipulation of ultrasound contrast agent microbubbles. He used the experimental configuration to demonstrate that microbubbles, stimulated by ultrasound, were capable of ‘micro-jetting’ into biological cells, as a drug delivery mechanism…
…and so his obsession with cavitation was born. Soon after graduating, Paul took an RCUK fellowship at the newly founded Institute of Medical Science and Technology (IMSaT), University of Dundee. From there he (eventually!) developed an independent research programme, studying bubble activity in high-intensity focused ultrasound (HIFU), for potential therapeutic applications. His research goal is to harness and control the power of cavitation for medical and industrial applications …he loves a challenge!
Jae received a BSc degree in computer science, an MEng degree in electronic engineering, and a PhD degree in interdisciplinary program of integrated biotechnology from the Sogang University, Seoul, Korea, in 2004, 2006, and 2012, respectively. From 2012 to 2014, he was a postdoctoral researcher at Medical Solutions Institute, Sogang Institutes of Advanced Technology.
Ms Miriam Jimenez Garcia is a 2nd year PhD student
Miriam has a background in Computer Science (she holds a 3-year Diploma degree as well as a 5-year Licentiate degree in Computer Science Engineering) from the University of Valladolid (Spain) and a M.Sc. in Biomedical Engineering from the University of Dundee.
In 2008, she obtained her Diploma in Computer Science Technical Engineering for Management, where she received First Class Honours in a diploma degree project titled “Development of a Control Architecture for a Surgical Robot”. She then obtained her Licentiate in Computer Science Engineering in 2012, with First Class Honours thesis titled “Generation of Timed Transition Diagrams for Time Constraints Representation in Healthcare Processes”. Miriam graduated in 2013 with an M.Sc. in Biomedical Engineering with thesis titled “Ultrasound-guided Focused Ultrasound Surgery”. This was her first encounter with a technique that truly sparked her interest, due to its wide range of potential applications in medicine.
She has just started her second year of PhD in IMSaT, under the direct supervision of Dr Paul Prentice. She will be particularly involved on the development of an FPGA-based rapid feedback control loop between detector and focused ultrasound source, to manipulate cavitation activity at sub-millisecond timescales.
Kristoffer was educated at the University of Bergen, Norway. During his MSc in Physics, he wrote a thesis with the title ‘Ultrasonic Manipulation of Particles and Spatio-Temporal Dynamics of Antibubbles’. Kristoffer initiated and successfully completed work regarded by multiple funding bodies to be of high quality. Consequently, he contributed with scientific work to multiple international scientific conferences during his MSc. Several scientific publications were authored by Kristoffer in this period; ‘Acoustically Active Antibubbles’, ‘Nonlinear Echoes from Encapsulated Antibubbles’, and ‘Ultrasonically Driven Antibubbles Encapsulated by Newtonian Fluids for Active Leakage Detection’. Kristoffer has an extensive knowledge and understanding of the physics of bubbles, and their potential applications. Hence, he is assigned the objective of shedding some theoretical light on cavitation clouds. A famous bongo drum player once said: ‘It doesn’t matter how beautiful your theory is, it doesn’t matter how smart you are. If it doesn’t agree with experiment, it’s wrong.’ Studying cavitation clouds with this philosophy a novel understanding of their fundamental nature, and potential application in medicine and industry will successfully be achieved.